full pbpk model using the simcyp population-based simulator version 17 (Simcyp)
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Simcyp
full pbpk model using the simcyp population-based simulator version 17
Full Pbpk Model Using The Simcyp Population Based Simulator Version 17, supplied by Simcyp, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/full+pbpk+model+using+the+simcyp+population-based+simulator+version+17/simulator+version+17/pm32184039-65-16-12
Average 90 stars, based on 1 article reviews
Full Pbpk Model Using The Simcyp Population Based Simulator Version 17, supplied by Simcyp, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/full+pbpk+model+using+the+simcyp+population-based+simulator+version+17/simulator+version+17/pm32184039-65-16-12
Average 90 stars, based on 1 article reviews
full pbpk model using the simcyp population-based simulator version 17 - by Bioz Stars,
2026-09
90/100 stars
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other:Article Title: Simple pharmacokinetic models accounting for drug monitoring results of atomoxetine and its 4-hydroxylated metabolites in Japanese pediatric patients genotyped for cytochrome P450 2D6. Article Snippet: Atomoxetine is an approved medicine for attention-deficit/hyperactivity disorder and a cytochrome P450 2D6 (CYP2D6) probe substrate.. Simple physiologically based pharmacokinetic (PBPK) models and compartment models were set up to account for drug monitoring results of 33 Japanese patients (6e15 years of age) to help establish the correct dosage for the evaluation of clinical outcomes.. The steady-state one-point drug monitoring data for the most participants indicated the extensive biotransformation of atomoxetine to 4-hydroxyatomoxetine under individually prescribed doses of atomoxetine. |